Epidiolex Vs CBD Oil

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Seizures are shared. Now hope is too. Experience the possibility of significant seizure reduction with EPIDIOLEX, the 1st and only FDA-approved prescription CBD used to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex in patients 1 year of age and older. See Important Safety Information. Epidiolex is a CBD-based pharmaceutical prescribed to treat epilepsy. Is it the same as CBD oil? Apparently not. Let’s dive into the differences between Epidiolex and CBD oil. My doctor has tried signing me up for the new Epidiolex CBD Oil. I have questions on these topics. Have

Seizures are shared.
Now hope is too.

Families share everything. For many, that includes the fears and frustrations of living with seizures. With seizure reduction from EPIDIOLEX, families can now share something else: hope.

EPIDIOLEX is the first and only FDA-approved prescription cannabidiol (CBD) to treat seizures associated with Lennox-Gastaut syndrome (LGS), Dravet syndrome, or tuberous sclerosis complex (TSC) in patients 1 year of age or older.

EPIDIOLEX results

EPIDIOLEX significantly reduced seizures in people living with LGS, Dravet syndrome, or TSC for whom multiple previous antiseizure medicines did not work well.

Getting started on EPIDIOLEX

Learn about getting your prescription and the insurance process, dosing, administration, and more.

Helpful resources

Learn more about CBD, and download a doctor discussion guide and other helpful tools and worksheets, including dosing and medication guides.

A series about navigating the complexities of living with epilepsy

Greg Grunberg hosts The Care Giver

Join Greg, actor and advocate for his son living with epilepsy, as he travels across the country to help tell the stories of caregivers of families living with rare forms of epilpesy. The caregivers get an unforgettable day of care and Greg gets to learn about their challenges and hopes along the way. The Care Giver series is full of incredible stories of caregivers from diagnosis to starting on EPIDIOLEX that will provide you strength and hope in knowing you’re not alone on this journey.

Important Safety Information

What is the Most Important Information I Should Know About EPIDIOLEX (cannabidiol)?
Do not take if you are allergic to cannabidiol or any of the ingredients in EPIDIOLEX. EPIDIOLEX may cause liver problems. Your doctor may order blood tests to check your liver before you start taking EPIDIOLEX and during treatment. In some cases, EPIDIOLEX treatment may need to be stopped. Call your doctor right away if…

Indications

What is EPIDIOLEX (cannabidiol)?
EPIDIOLEX is a prescription medicine that is used to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex … in patients 1 year of age and older. It is not known if EPIDIOLEX is safe and effective in children under 1 year of age.

Important Safety & Indications Important Safety Information & Indications

What is the Most Important Information I Should Know About EPIDIOLEX (cannabidiol)?

Do not take if you are allergic to cannabidiol or any of the ingredients in EPIDIOLEX.

EPIDIOLEX may cause liver problems. Your doctor may order blood tests to check your liver before you start taking EPIDIOLEX and during treatment. In some cases, EPIDIOLEX treatment may need to be stopped. Call your doctor right away if you start to have any of these signs and symptoms of liver problems during treatment with EPIDIOLEX :

  • loss of appetite, nausea, vomiting
  • fever, feeling unwell, unusual tiredness
  • yellowing of the skin or the whites of the eyes (jaundice)
  • itching
  • unusual darkening of the urine
  • right upper stomach area pain or discomfort

EPIDIOLEX may cause you to feel sleepy, which may get better over time. Other medicines (e.g., clobazam) or alcohol may increase sleepiness. Do not drive, operate heavy machinery, or do other dangerous activities until you know how EPIDIOLEX affects you.

Like other antiepileptic drugs, EPIDIOLEX may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call a healthcare provider right away if you have any signs of depression or anxiety, thoughts about suicide or self-harm, feelings of agitation or restlessness, aggression, irritability, or other unusual changes in behavior or mood, especially if they are new, worse, or worry you.

Take EPIDIOLEX exactly as your healthcare provider tells you. Do not stop taking EPIDIOLEX without first talking to your healthcare provider. Stopping a seizure medicine suddenly can cause serious problems.

What Else Should I Know When Taking EPIDIOLEX?

The most common side effects of EPIDIOLEX include increase in liver enzymes, sleepiness, decreased appetite, diarrhea, fever, vomiting, feeling very tired and weak, rash, sleep problems, and infections.

EPIDIOLEX may affect the way other medicines work, and other medicines may affect how EPIDIOLEX works. Do not start or stop other medicines without talking to your healthcare provider. Tell healthcare providers about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and cannabis-based products.

What Additional Information Applies to Women?

If you are pregnant or plan to become pregnant, EPIDIOLEX may harm your unborn baby. You and your healthcare provider will have to decide if you should take EPIDIOLEX while you are pregnant.

If you become pregnant while taking EPIDIOLEX, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry (by calling 1-888-233-2334). The purpose of this registry is to collect information about the safety of antiepileptic medicines during pregnancy.

Because many medicines like EPIDIOLEX are passed into breast milk, talk to your healthcare provider about the best way to feed your baby while taking EPIDIOLEX.

What is EPIDIOLEX (cannabidiol)?

EPIDIOLEX is a prescription medicine that is used to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex in patients 1 year of age and older.

It is not known if EPIDIOLEX is safe and effective in children under 1 year of age.

Please refer to the EPIDIOLEX Medication Guide and Instructions for Use for additional important information.

You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. You may also contact Jazz Pharmaceuticals at 1-833-424-6724.

Important Safety Information

What is the Most Important Information I Should Know About EPIDIOLEX (cannabidiol)?
Do not take if you are allergic to cannabidiol or any of the ingredients in EPIDIOLEX. EPIDIOLEX may cause liver problems. Your doctor may order blood tests to check your liver before you start taking EPIDIOLEX and during treatment. In some cases, EPIDIOLEX treatment may need to be stopped. Call your doctor right away if…

Indications

What is EPIDIOLEX (cannabidiol)?
EPIDIOLEX is a prescription medicine that is used to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex … in patients 1 year of age and older. It is not known if EPIDIOLEX is safe and effective in children under 1 year of age.

Important Safety & Indications Important Safety Information & Indications

What is the Most Important Information I Should Know About EPIDIOLEX (cannabidiol)?

Do not take if you are allergic to cannabidiol or any of the ingredients in EPIDIOLEX.

EPIDIOLEX may cause liver problems. Your doctor may order blood tests to check your liver before you start taking EPIDIOLEX and during treatment. In some cases, EPIDIOLEX treatment may need to be stopped. Call your doctor right away if you start to have any of these signs and symptoms of liver problems during treatment with EPIDIOLEX :

  • loss of appetite, nausea, vomiting
  • fever, feeling unwell, unusual tiredness
  • yellowing of the skin or the whites of the eyes (jaundice)
  • itching
  • unusual darkening of the urine
  • right upper stomach area pain or discomfort
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EPIDIOLEX may cause you to feel sleepy, which may get better over time. Other medicines (e.g., clobazam) or alcohol may increase sleepiness. Do not drive, operate heavy machinery, or do other dangerous activities until you know how EPIDIOLEX affects you.

Like other antiepileptic drugs, EPIDIOLEX may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call a healthcare provider right away if you have any signs of depression or anxiety, thoughts about suicide or self-harm, feelings of agitation or restlessness, aggression, irritability, or other unusual changes in behavior or mood, especially if they are new, worse, or worry you.

Take EPIDIOLEX exactly as your healthcare provider tells you. Do not stop taking EPIDIOLEX without first talking to your healthcare provider. Stopping a seizure medicine suddenly can cause serious problems.

What Else Should I Know When Taking EPIDIOLEX?

The most common side effects of EPIDIOLEX include increase in liver enzymes, sleepiness, decreased appetite, diarrhea, fever, vomiting, feeling very tired and weak, rash, sleep problems, and infections.

EPIDIOLEX may affect the way other medicines work, and other medicines may affect how EPIDIOLEX works. Do not start or stop other medicines without talking to your healthcare provider. Tell healthcare providers about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and cannabis-based products.

What Additional Information Applies to Women?

If you are pregnant or plan to become pregnant, EPIDIOLEX may harm your unborn baby. You and your healthcare provider will have to decide if you should take EPIDIOLEX while you are pregnant.

If you become pregnant while taking EPIDIOLEX, talk to your healthcare provider about registering with the North American Antiepileptic Drug Pregnancy Registry (by calling 1-888-233-2334). The purpose of this registry is to collect information about the safety of antiepileptic medicines during pregnancy.

Because many medicines like EPIDIOLEX are passed into breast milk, talk to your healthcare provider about the best way to feed your baby while taking EPIDIOLEX.

What is EPIDIOLEX (cannabidiol)?

EPIDIOLEX is a prescription medicine that is used to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex in patients 1 year of age and older.

It is not known if EPIDIOLEX is safe and effective in children under 1 year of age.

Please refer to the EPIDIOLEX Medication Guide and Instructions for Use for additional important information.

CBD Oil vs Epidiolex — Which Is Better for Epilepsy?

The approval of Epidiolex in June 2018 signified a turning point in the treatment and management of seizures. Since the FDA-approved drug has CBD as its major component, its inclusion into the medical space as a prescription drug convinced even CBD’s skeptics of its potential

However, are Epidiolex and CBD Oil the same?

Proponents assume that since both products contain Cannabidiol, they must have the same uses. However, ongoing research does not support this claim.

This article seeks to spell out the differences between Epidiolex and CBD Oil, their principal pharmacological effects, side effects, and how best to increase the former and subdue the latter.

About Epilepsy

Epilepsy is a chronic non-communicable disease of the nervous system that affects about 50 million people worldwide. The condition is marked by unprovoked seizures, during which an individual loses voluntary control of the entire body or just a part of the body.

One seizure does not make an epileptic. According to the World Health Organisation, an individual must have had at least two seizures in his lifetime to be diagnosed with epilepsy. Epilepsy is a sensitive condition; the risk of premature death in epileptics is three times that of an average person. Statistics declare that 70% of epileptics can live seizure-free with proper management.

Common medications used to manage epilepsy include anti-epileptic drugs (AEDs) such as Clonazepam, Diazepam, Valproic acid, which usually present with side effects like lack of energy, drowsiness, tremors, headaches, and hair loss.

CBD is a potent anti-seizure medication that has found its use in some particular kinds of epilepsy; the drug-resistant Dravet Syndrome, Lennox-Gastaut Syndrome which plagues infants, and in Tuberculosis Sclerosis Complex. CBD products present with milder side effects than typical AEDs and are much more tolerable.

The only FDA-approved brand of CBD for managing seizures is Epidiolex. Nonetheless, other formulations containing organically-sourced CBD will have similar effects on seizures. The potency of CBD Oil against a seizure is dependent on its dose, form, and preparation.

What is CBD?

CBD stands for cannabidiol. It’s one of the cannabinoids found in the Cannabis Sativa plant. CBD is not psychoactive like tetrahydrocannabinol (THC), its sister component. This makes it more appealing when it comes to relieving pain and other symptoms without psychoactive side effects, and is suitable for children above the age of two.

Cannabidiol is one of the most active ingredients of medical cannabis, second only to THC. You can derive it directly from the marijuana flowers, or by using larger amounts of hemp plants. It can also be manufactured in a laboratory. Cannabidiol comes in different forms such as oils, vapes, creams, extracts, and capsules.

Research on human and animals have suggested some benefits of CBD such as:

  • Anti-seizure properties
  • Neuroprotective effects
  • Anti-acne and Anti-inflammatory
  • Anti-cancer
  • Fights anxiety disorders
  • Lowers cravings for tobacco and heroin
  • Lowers high blood pressure
  • Improves sleep

What is Epidiolex?

Epidiolex is an extract from cannabis that contains 99% CBD that has been purified and is prescribed for medical purposes.

Although it contains no THC, as of 2018, it was placed on the list of controlled drugs and classified as a Schedule V prescription drug. This means that the regulatory body suspected that the drug may be subject to misuse by individuals seeking the psychoactive effects of THC.

As of 2020, Epidiolex was taken off the controlled drugs list, and pharmacists were free to dispense without retaining the prescription. Epidiolex remains a prescription-only drug. However, this legislation makes it easier to refill when it runs out.

Ingredients of Epidiolex

The formula of Epidiolex includes the following ingredients:

  1. Cannabidiol: the exact mechanism through which cannabidiol halts seizures remain unknown to scientists. One proposed mechanism involves the activation of the CB1 receptors of the endocannabinoid system, which are concentrated in the brain, and sparsely distributed in the periphery.
  2. Sucralose: Sucralose is an artificial sweetener. It has almost no calories and is 600 times sweeter than real sugar. Sucralose is used in ice cream and yogurt.
  3. Sesame seed oil: Sesame oil is edible vegetable oil. It is derived from sesame seeds. Sesame oil contains omega-3 and omega-6 fatty acids. It provides the benefit of protecting skin from sunburn and managing inflammation.
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What is CBD Oil?

CBD oil is a viscous extract with high concentrations of CBD. The extract is diluted in a carrier oil, such as MCT oil or hemp seed oil to improve its bioavailability and speed up absorption. People use it for daily supplementation as well as to treat or manage the aforementioned health conditions.

Ingredients of CBD Oil

These are the following main ingredients:

  1. Hemp: A hemp flower is an unprocessed bud from the hemp plant. Hemp has a higher concentration of cannabidiol and a lower level of tetrahydrocannabinol.
  2. MCT Oil: MCT oil is a supplement made from medium-chain triglycerides. It is easily oxidized and breaks down rapidly to release energy. The oil, which can be found in coconut and palm oil, is rich in antioxidants and anti-inflammatory effects by activating neutrophils and mitochondrial reprogramming.

Comparing CBD Oil and Epidiolex: Epilepsy Treatment

Epidiolex in the Treatment of Epilepsy

Epidiolex is the first FDA-approved drug that is a CBD-derived medication for the treatment of epilepsy.

The FDA approved Epidiolex for the treatment of two severe and rare forms of epilepsy in patients two years of age and older — Lennox-Gastraut syndrome and Dravet syndrome. Epidiolex is also approved to treat seizures associated with tuberous sclerosis complex.

The job of the FDA is to protect public health by ensuring the safety, effectiveness, and security of human and veterinary drugs, vaccines, and other biological products for human use and medical services. First of all, the manufacturers of a product conduct laboratory, animal, and clinical testing. Then, the FDA reviews the results of the testing and grants approval.

Three clinical trials involving 516 patients with Lennox-Gastaut syndrome and Dravet syndrome studied the effectiveness of Epidiolex. In one of these trials, Epidiolex was combined with other anti-seizure medications. Compared to a placebo, Epidiolex was more effective in the reduction of seizures.

CBD Oil in the Treatment of Epilepsy

CBD oil is a mixture of Cannabidiol with a carrier oil. CBD oils that contain other compounds such as supportive cannabinoids, terpenes, and traces of THC are labeled as full-spectrum by manufacturers. The presence of these supporting compounds boosts the effect of CBD, a mechanism called the entourage effect. This phenomenon doesn’t occur in the highly purified Epidiolex.

CBD oil may help in treating some seizure symptoms but it has some side effects. CBD Oil typically comes as a tincture, with a dosage of 25-50mg of CBD per ml. The CBD market isn’t regulated like the pharmaceutical industry, so there’s no standardization among products, both when it comes to potency and purity. Therefore, it’s difficult to evaluate the efficacy of specific dosages.

More research still needs to be carried out to understand the risks and benefits of CBD oil.

Which is Better in the Treatment of Epilepsy?

The option of Epidiolex and CBD Oil gives patients and caretakers a chance to individualize their regimen. The best pick would depend on each patient’s individual circumstances.

CBD oil has a broader spectrum of activity and fewer side effects. It may treat other coexisting conditions such as acne and inflammation, as opposed to the rash occasionally associated with Epidiolex use. Even so, always consider the effect of seizure relief. At the appropriate dosage, CBD Oil is just as potent as Epidiolex.

What to Consider When Choosing Between Epidiolex vs CBD Oil

Regulations

The FDA is yet to approve any commercial CBD brands for the treatment of epilepsy. Epidiolex is a prescribed drug that has gone through well-controlled clinical trials, has been reviewed and approved by the Food and Drug Administration (FDA) to treat Lennox-Gastraut and Davet syndrome. You may get a prescription for Epidiolex, and purchase it at the nearest pharmacy.

CBD oils are recommended by doctors and can be purchased from online or physical stores. You don’t need a prescription for such products.

Safety

FDA studies suggest Epidiolex has been proven to be safe. Epidiolex is a cannabis extract made up of 99% CBD that has been purified. It also contains no tetrahydrocannabinol. THC is a principal psychoactive component of cannabis with a “high” effect.

CBD oil may contain other cannabinoid compounds and some contaminants. The FDA does not regulate CBD products, so CBD oils are not proven to be safe. The concentration of THC may vary with the brand.

Effectiveness

According to Dr. Devinsky, a professor of neurology, neurosurgery, and psychiatry at the NYU Grossman school of medicine and director of NYU Langone’s Comprehensive Epilepsy Center, “The approval of Epidiolex or cannabidiol is a landmark in medicine. It is the first time such a medication, based on a cannabis plant, has been approved and scientifically established to be an effective treatment in the United States.” The pharmacological actions of CBD are not fully understood. However, Dr. Devinsky says, “We do understand some of how it helps to control seizures (by working) on a receptor system that no other drug touches.”

More research still needs to be carried out to understand the effectiveness of CBD oil.

Side Effects

Clinical trials carried out on Epidiolex suggest significant side effects were experienced by some of the participants like fever, vomiting, diarrhea, lethargy, fatigue, and drowsiness. Epidiolex may also lead to a change in liver function, jaundice, unusual darkening of the urine, and right upper abdominal pain.

CBD, the main component of CBD oil, is well-tolerated and its effects are considered mild Some of these adverse reactions include abnormalities in liver function, drowsiness, diarrhea, and dry mouth. In some studies, some patients experienced an increase in seizures with CBD. CBD Oil may interact with other medications, such as blood thinners.

Affordability

It can be expensive to purchase Epidiolex. However, insurance may cover it in certain regions. The Epidiolex Copay Savings Program is eligible to legal residents of the United States or Puerto Rico. Some people who lack access to these privileges opt to buy CBD products from stores as an OTC alternative.

How to Use Epidiolex vs CBD oil

How to Use Epidiolex

Epidiolex is a liquid pharmacological drug. It is administered orally. The required dosage of Epidiolex depends on body weight and symptom severity.

The dosage based on a child’s body weight:

  1. Starting dosage: 2.5 milligrams per kilogram (mg/kg) taken twice daily per oral.
  2. Maintenance dosage: 5 mg/kg taken twice daily per oral.
  3. Maximum dosage: 10 mg/kg taken twice daily per oral.

How to use CBD oil

Most CBD oils come in bottles with a dropper. There are no guidelines for the proper administration but there are methods of using CBD oil. CBD oil is administered sublingually. place a few drops under the tongue and retain for 30 to 60 seconds without swallowing. The dose may be 5mg-25mg daily depending on what you are treating.

Interactions Between CBD and Medications

Certain side effects may occur when CBD is used with other drugs and medications such as:

  • Antipsychotics
  • Benzodiazepines
  • Clonazepam
  • Fluoxetine
  • Erythromycin
  • Clarithromycin
  • Calcium channel blockers
  • Carbamazepine
  • Ketoconazole
  • Fentanyl
  • Rifampin

CBD inhibits some enzymes of the large family of CYP450 and alters the way they metabolize certain drugs. It’s a similar mechanism to the one demonstrated by grapefruit juice. When taken together with other medications, CBD may either decrease or increase its concentration in the bloodstream — leading to toxicity or subtherapeutic effects depending on the type of interaction.

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If you take any medications, talk to your doctor before adding CBD oil to your routine. Doing so will help you find the right timing for both compounds, as well as the dose to avoid interactions.

Key Takeaways on CBD vs Epidiolex

The major difference between the purified and FDA-approved Epidiolex and CBD Oil brands is that Epidiolex contains 99% CBD and no other cannabinoids. CBD oils, on the other hand, contain supportive cannabinoids that enhance their pharmacological activity. On the flip side, CBD Oils may contain contaminants and psychoactive compounds if they’re improperly manufactured and not tested by a third-party laboratory.

CBD oils also vary in terms of potency, appearance, and taste, based on brand. This may be desirable when a wider range of options positively affects treatment results.

People now have the choice of using Epidiolex or CBD oil to treat epilepsy. You need to know what they are and how they work before choosing your treatment option. If you would like to explore the prescribed medication, Epidiolex, or store-bought CBD oil, talk to your doctor first.

Sources:

  1. Esposito, L. (2020), CBD Oil for Treating Epilepsy, U.S News and World Report L.P.
  2. FDA, (2018), FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy, FDA News Release.
  3. Iffland, K., Grotenhermen, F. (2017), An Update on Safety and Side effects of Cannabidiol: a Review of Clinical Data and Relevant Animal Studies, Mary Ann Liebert, Inc. 2(1), 139-154.
  4. World Health Organization (2022). Epilepsy. WHO.int. Retrieved from: [1]
  5. Abu-Sawwa, R., & Stehling, C. (2020). Epidiolex (Cannabidiol) Primer: Frequently Asked Questions for Patients and Caregivers. The journal of pediatric pharmacology and therapeutics: JPPT: the official journal of PPAG, 25(1), 75–77. [2]
  6. Martinez, M. (2021). CBD May Help People with Epilepsy Better Tolerate Anti-Epilepsy Medications. John’s Hopkins Medicine. Retrieved from: [3]
  7. Yu, Go, & Kim. (2019). Medium Chain Triglyceride (MCT) Oil Affects the Immunophenotype via Reprogramming of Mitochondrial Respiration in Murine Macrophages. Foods, 8(11), 553. [4]
  8. Singh, J., & Antimisiaris, M. F. (2020). Epidiolex-induced skin rash. Epileptic disorders: international epilepsy journal with videotape, 22(4), 511–514. https://doi.org/10.1684/epd.2020.1189
Livvy Ashton

Livvy is a registered nurse (RN) and board-certified nurse midwife (CNM) in the state of New Jersey. After giving birth to her newborn daughter, Livvy stepped down from her full-time position at the Children’s Hospital of New Jersey. This gave her the opportunity to spend more time writing articles on all topics related to pregnancy and prenatal care.

CBD Oils Vs. Epidiolex

My doctor has tried signing me up for the new Epidiolex CBD Oil. I have questions on these topics. Have any of you tried the new Epidiolex and haven’t or had any seizures while taking this? What is the difference between this specific “Epidiolex” and other CBD Oils that could be offered?

CBD oil vs.Epidiolex
The answer is its purified CBD vs.purchasing CBD oil from a collective or a dispensary which is Whole Plant CBD oil.
The other big difference is the mg Epidiolex is 100mg/ML most CBD oil is not that potency.
It is usually 25 to 50mg per ML.
Epidiolex is a consistent strain & dosage.
CBD oil from a collective is usually a mix of high CBD strains and low THC.
There is no proof one is better than the other. The only difference is one can be prescribed by your doctor and your insurance may pay for it.
So far the Epidiolex has worked in controlling the seizures but it’s only been 2 weeks.
Also the Epidiolex has Strawberry flavoring and Sucralose in it.
It tastes and smells awful.Because it was designed for mostly young kids to take orally.
Whole Plant CBD oil tastes like cannabis with whatever carrier oil it is in like MCT oil or olive oil.
CBD oil is very helpful in controlling seizures but a THC Vape cartridge & pen or battery will literally stop a seizure if you have enough time to start vaping and STOP the seizure.
Get a THC vape cartridge and use it when you feel a seizure coming it most likely will stop it.
The only thing about the Vape cartridge is you need to act quickly the THC needs to get in before the seizure begins

the shorten word for cbd is cannabidiol (cannabis). epidiolex is cannabis oil. its just a brand name on drs. there is another site called charlottes web hemp (www.cwhemp.com) where a really young girl named charlotte had grand mals a lot of times a day and after the cbd oil 1 kinda seizure a couple of months to a year (like the epidiolex girl did).
the only things are drs order epidiolex and cwhemp order online.
there is others one called www.koi.com (like the fish). there is no thc and pure ingredients. they are tested from a third party and sold in stores and online.
so the cbd oil vs epidiolex is the same thing. i just used the koi because its local vape store and i done my research.
as for the question. i have not tried this type because its all the same but different packaging. there is no difference between epiliolex, cwhemp, and koi.

I was just approved to take CBD oil. I had to get a medical marijuana licence, which is only valid for a year before I have to renew it. I also got the prescription I wanted. With regards to the Epidiolex unfortunately it isn’t available in Canada. I’ve been reading everything on it and it sounds good though.

We don’t get the epidiolex here in Canada however, I have been taking CBD oil and have am having 20+ less seizures a month I was having up to 36 a month. I can’t believe I’m going to say this but thanks to the liberals marijuana is now legal here, which has enabled me to be able to take the CBD oil. For that I’m thankful. There were nights I was having up to 6 seizures a night and now I don’t have more than 2 a night. Both myself, friends, and my family are amazed at the difference the oil has had.

I have not found a brand that works for me. Breeders cross high resin (high THC) cannabis types with hemp to reduce the THC to below 0.3% THC while retaining or increasing the CBD levels. Unfortunately, in this process, many of the other cannabinoids have been bred out of the high resin types. CBD is not the only beneficial cannabinoids. ‘Pure CBD’ has never had a notably beneficial effect on me, but full extracts have. Companies worldwide are trying to reintegrate these other cannabinoids into low THC lines. Let’s hope that big pharma doesn’t hamstring this process!

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