Can I Give My Dog Prednisone And CBD Oil

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Have you ever been prescribed steroids for your pet? What if I told you there is a natural alternative? Full Spectrum Hemp CBD vs Steriods! If your dog is suffering from irritation, inflammation, or even severe disease, your vet might recommend a drug called Prednisone. This blog will explore the potential uses, side effects, dosage, and natural alternatives…

Steroids vs. CBD: A Topic of Truths and Transitions

Chances are that most humans and pets have been prescribed a steroid medication at some point in their life for treatment of one or more medical conditions. Whether it be for inflammation, allergies, or another type of illness, injectable and oral steroids have been applied by doctors and veterinarians for decades as a part of treatment plans due to their effectiveness in addressing numerous symptoms quickly and effectively. However, although the relatively fast effects felt by starting a steroid may be impressive, long-term use can and very often lead to serious side effects, both in humans and pets. Moreover, despite newer age doctors trying to move away from heavy use and dependence on steroids, this class of medications is still to this day used more than it should be, given that we know now what they likely lead to over time.

In comparison, CBD and other cannabis-based therapies have recently been found to effectively address a majority of the same symptoms steroids remediate, but do not tend to cause any of the same adverse long-term side effects steroids come with. Therefore, there is a huge potential promise in considering CBD as a legitimate therapeutic substitution for steroids when developing a safe and effective therapeutic treatment plan. Ultimately, when a life of longevity, health, and happiness is the long-term goal, understanding the ramifications and alternatives to steroid therapy is critical for the well-being of patients, including your pet.

Table of Contents

What are Steriods?

The term “steroid” simply describes a class of molecules that have a variety of influences and effects within an animal’s body. Specifically, there are “natural steroids” which our bodies make on their own, and “synthetic steroids” that are produced in laboratories that overlap with our internal bodily systems.

Steroids became widely popular in the 1940’s for inflammatory conditions . Corticosteroids in particular were and continue to be used to treat symptoms associated with arthritis and other degenerative musculoskeletal conditions. In fact, in 1950, the Nobel Prize for Physiology or Medicine went to Dr. Philip Hench, Edward Calvin Kendall, and Tadeus Reichstein for the discovery of cortisone and its applicable uses with rheumatoid arthritis.

Since their discovery and explosion onto the medical scene, steroids eventually became widely over-prescribed, as they were viewed as the “miracle drug” that could help with any and all conditions in conjunction with those initially known. However, as the repercussions of long-term use then began to surface as well, a shift towards healthier, long-term substitutions has slowly begun. Many doctors and veterinarians now only prescribe steroids for short-term applications and rely on multimodal therapies to promote long-term control of the underlying illness(es). However, many other medical professionals have not yet adopted this pattern, and still use steroids more often than is thought to be safe or required. T here are a small number of situations where steroids must be used for long-term immunosuppression (including some refractory autoimmune diseases and Addison’s Disease), but again, these are rather uncommon. Unless your pet has one of these conditions, steroids should be considered a short-term solution only.

The most common steroids prescribed by most veterinarians are prednisone, prednisolone, hydrocortisone topicals, and TEMARIL-P . Steroids do, in fact, reduce inflammation in the body, but not without a cost. The most common side effects of early steroid use include polyuria (excessive urination), polydipsia (excessive thirst), polyphagia (excessive signs of hunger despite not actually requiring more food), and panting. Steroids are also well-known for their serious, and sometimes dangerous, side effects including:

  • Weight gain
  • Salt and fluid retention
  • Diabetes
  • Cardiac Problems (Heart)
  • Increased secondary infection risk
  • Slower wound healing
  • Loss of muscle mass
  • Hepatic Problems (Liver)

If any of the following serious side effects occur, stop giving Temaril-P and seek emergency veterinary medical attention ; an allergic reaction ( difficulty breathing; swelling of the lips, tongue or face; hives ). Trimeprazine can cause drowsiness, tremors and muscle weakness . Prednisolone may cause symptoms of Cushing’s disease which include increased thirst, urination and hunger as well as vomiting and diarrhea . Other side effects may also occur. Talk to your veterinarian about any side effect that seems unusual or bothersome to your pet. Do not give any other over the counter or prescription medications, including herbal products, during treatment with Temaril-P without first talking to the veterinarian. Many other medications can interact with Temaril-P resulting in side effects or altered effectiveness. These include sedatives, anesthetics, pain medications, epinephrine and procaine.”

As stated above, there are few cases where lifetime use of steroids is necessary. But, in the majority of cases where it is not a necessity, the body will become susceptible to developing one or more of the many side effects listed, and will also be subject to dependency and severe withdrawal effects if steroid therapies are discontinued too quickly. That’s why doctors generally advise a gradual tapering protocol off of steroids toward the end of a long-term treatment plan. Ultimately, if a steroid has been used for more than 7 days, then it is not advisable to stop this medication abruptly without the supervision of a medical professional, as this can prove detrimental to your pet’s health as well.

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What are Steriods Used for?

Oral steroids are the most commonly prescribed medication for dogs (and us). These medications again are synthetic steroids, meaning they are not naturally produced by our body . They are most often prescribed to treat inflammatory conditions, skin conditions, non-infectious respiratory diseases, and degenerative neuromusculoskeletal conditions.

According to Dr. Gary Richter , “ steroids are some of the most powerful anti-inflammatory medications available .” Because of this, they tend to be a commonplace treatment for pets with skin and respiratory conditions. Dr. Richter continued to state, “ despite steroids’ ability to reduce inflammation, their long term side effects far outweigh their benefits .”

Steroid-Sparing Methods

CBD is being researched as a ‘steroid-sparing option.’ A study published in Current Neuropharmacology indicated CBD has therapeutic benefits for both people and pets who suffer from chronic pain. There is an abundance of compounds found to reduce inflammation in both us and our pets. The most common phytocannabinoids found in the Cannabis plant, THC and CBD, both possess anti-inflammatory properties. Other minor cannabinoids, including CBG, CBC, and THCV were also found to provide anti-inflammatory properties as well.

According to Future Medicinal Chemistry , “ cannabinoids have exhibited significant potential to be used as novel anti-inflammatory agents and specific targeting of CB2 receptors holds the promise of mediating immunosuppressive effects without exerting psychotropic side effects.”

A Baylor College of Medicine study, using In vitro and in mouse models, found that CBD significantly attenuated the production of proinflammatory cytokines IL-6 and TNF-α while elevating levels of anti-inflammatory IL-10. In the veterinary study, CBD significantly decreased pain and increased mobility in a dose-dependent fashion among animals with an affirmative diagnosis of OA.

According to a veterinarian named Steven Katz , who is one of only a few doctors applying CBD-based therapies in practice, “our experience in my clinic has shown cannabidiol (CBD) is an effective treatment in reducing inflammatory response . We have a passion for improving dogs’ quality of life, and we look forward to learning all we can about therapeutic methods to achieve this.”

The Ultimate Question: Steriods vs. CBD

First things first: If you are reading this and your dog is already taking steroids, it’s absolutely critical the regimen is not stopped immediately. Never attempt to taper this medication without the supervision of a licensed veterinarian.

Taking a full-spectrum CBD-based product in combination with a steroid, like prednisone, will most likely (not guaranteed) not result in any detrimental adverse effects. Although both compounds are broken down by the liver, taking both at the same time is unlikely to cause “liver overload” unless the liver is already unhealthy (which would have been or can only be determined by submitting bloodwork with your veterinarian). If the liver is already “sick” then there may be hypothetical concerns regarding administering both at the same time, even though research up to this point has not proven such statements. The reason for this is because research indicates that CBD and other cannabis-based molecules are broken down by the “cytochrome p450 enzyme” group located in the liver, and that CBD specifically inhibits a component of the activity of a particular enzyme (CYP3A4) which is used by the body to break down numerous other molecules. The effects of this are still not entirely known, but with an unhealthy liver, it is highly advised to be more careful when considering any extra stress it may cause on this organ. We do know that Prednisone does cause liver “induction” resulting in numerous secondary effects, both on the liver’s functioning ability and its ability to handle other molecules simultaneously, such as CBD and the other active compounds in a full-spectrum product. Again though, each animal is an individual, and therefore, each case must be addressed individually before making any decisions or conclusions.

Of course, given what we know about steroids and CBD, we should all desire to get more pets off of long-term steroid use, and if appropriate, use a properly-vetted Full Spectrum Hemp CBD-based therapy to address the conditions steroids were originally applied for. But, this transition must be done responsibly. The overall goal is and should always be to promote a lifestyle of optimum healthiness and happiness. With the proper diet, natural supplements, and safe remedies in times of illness like a properly vetted full-spectrum CBD-based product, there is an opportunity to enhance and maintain your pet’s overall well-being without abusing and over-using pharmaceuticals, in an age where pharmaceuticals still seem to be king.

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Dr. Zac Pilossoph

Dr. Zac Pilossoph, a Long Island, NY born, nationally recognized veterinary medical professional, a top graduate of Tufts University Veterinary School of Medicine with post-graduate focused training in E/CC and Neurology/Neurosurgery at two of the most recognized programs in the country, and a young multidimensional serial entrepreneur, has rapidly and collaboratively helped promote a new wave of global evolution and individual empowerment in more ways than one. In addition to developing and launching several novel platforms in the veterinary and mental health fields, he is now quickly joining some of the most reputable leaders in the cannabis education and innovation space. Dr. Pilossoph is determined to synergize with colleagues, allowing evidence-based information to fuel a rapidly expanding industry. As one of the world’s most proactive cannabis-focused experts in his respective industry, Dr. Pilossoph provides tremendous value by delivering non-bias, harm reduction education, via both large-scale speaking engagements and individualized consultations, to the global cannabis pet and vet industry. Further, he is a Certified CBD Professional Educator through the CBD Training Academy and has started a nationally influential multi-tiered cannabis brokerage firm titled Excelsior Honour Associates. Lastly, he acts as a consultant for the CBD product space in order to impart as much quality, control, and consistency across the industry as much as possible. Ultimately, through candid education, fierce collaboration, and constructive evolution, Dr. Pilossoph is reversing stigmas and advancing the safe and effective consideration of cannabis into society, for all creatures on Earth.

Prednisone For Dogs: Side Effects, Dosage, And Alternatives

If your dog is suffering from irritation, inflammation, or even severe disease, your vet might recommend a drug called Prednisone.

This blog will explore the potential uses, side effects, dosage, and natural alternatives to Prednisone for dogs.

Table Of Contents

  • What is prednisone?
  • Prednisone vs. Prednisolone
  • What is prednisone used for in dogs?
  • Dosage of prednisone for dogs
  • Types of prednisone
  • Prednisone for dogs side effects
  • Is it safe for dogs?
  • Are there any drug interactions?
  • Cost
  • Are there any prednisone alternatives for dogs?

What is Prednisone?

Prednisone is a synthetic corticosteroid (steroid) used to treat various conditions in both humans and animals. It’s primarily used as an anti-inflammatory drug for dogs with allergies, irritation, infections, pain, and even cancer.

Prednisone vs. Prednisolone

The terms Prednisone and prednisolone are sometimes used interchangeably. They can both be used for the same conditions but are not the same.

Prednisolone is the active metabolite of Prednisone. It goes into effect as soon as it crosses the cell membrane of your dog’s body.

Prednisone is a cortisone derivative that will metabolize into prednisolone in the liver. It needs to be in the active form to cross the cell membrane and function properly. It can still be prescribed like prednisolone, but the dosage may differ.

What is Prednisone used for in dogs?

Prednisone for dogs is primarily used for emergencies or anti-inflammatory diseases.

Prednisone will often be given to dogs suffering from the following conditions:

There are many other situations in which prednisone can be prescribed, so this list is not exhaustive.

Dosage of Prednisone for dogs

The dosage for Prednisone depends on what condition your dog has, how much they weigh, and what type of Prednisone you’re using.

An ideal dosage would be 0.5 milligrams per pound of body weight each day for anti-inflammatory effects. But if you need to suppress your dog’s immune system, you should give 1 milligram per pound. The chart below calculates the average dosages using this information.

Weight (lbs) Daily Dosage (mg)
10 5-10
20 10-20
30 15-30
40 20-40
50 25-50
60 30-60
70 35-70
80 40-80
90 45-90
100 50-100

Prednisone should only be given to your dog for a few days before they’re weaned off of it. Some vets might even recommend giving it every other day or every few days instead to lessen the risks.

Types of Prednisone

Prednisone isn’t always given in the same form. There are a few different options that could be recommended for dogs.

Most commonly, Prednisone will be given to your dog as an oral tablet or liquid. The pills most commonly come in 10 mg to 20 mg tablets, while the liquid comes in 10 mL to 60 mL bottles. You can distribute both of these types with your dog’s food.

In some cases, your vet might administer the medicine as an injection. If the inflammation is around your dog’s eyes, you can opt to use prednisone eye drops for dogs instead. These more obscure options will have different dosages, so listen closely to what your vet advises.

All forms of this medicine will start working within one or two hours. So, you should start noticing improvements shortly after using it.

Prednisone for dogs side effects

Prednisone, like other steroids, can have side effects after use. Some minor side effects are quite common and will go away after your dog stops taking the drug. If your dog is taking the medication for longer periods or in higher doses, the side effects might be more severe.

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Common side effects

  • Drinking more often
  • More frequent urination
  • Larger appetite

Serious side effects

  • Vomiting
  • Diarrhea
  • Lethargy
  • Increased risk of infection
  • Behavior changes
  • Diabetes
  • Cushing’s disease

Is it safe for dogs?

Yes, Prednisone is safe for dogs, but like any medication, there are risks involved. Don’t use it for dogs who are allergic to it or dogs with viral infections, ulcers, tuberculosis, Cushing’s disease, or systemic fungal infections (unless it’s being used to treat Addison’s disease).

Use the drug with caution for dogs with diabetes, heart disease, osteoporosis, cataracts, high blood pressure, or kidney disease. It should only be used in emergencies for younger animals and pregnant animals because it can stunt growth or cause ulcers.

If you need to use Prednisone for your dog, always follow your vet’s instructions closely. Never abruptly stop the medication, but instead, slowly transition off of it.

Are there any drug interactions?

The following medications could be dangerous if used with Prednisone or prednisolone:

  • Amphotericin B
  • Anticholinesterase
  • Aspirin
  • Barbiturates
  • Bupropion
  • CBD
  • Cholestyramine
  • Cyclophosphamide
  • Cyclosporine
  • Digoxin
  • Ephedrine
  • Estrogens
  • Insulin
  • Ketoconazole
  • Macrolide antibiotics
  • Mycophenolate
  • Non-steroidal anti-inflammatory drugs (NSAIDs),
  • Phenobarbital
  • Rifampin
  • Warfarin

To avoid any complications, discuss your dog’s medications with your vet beforehand. This drug isn’t generally considered dangerous for dogs, but it can be if not used carefully.

The Prednisone cost for dogs depends on the type you use, the amount you need, and where you purchase it. Prednisone tablets usually come in 1-milligram to 50-milligram tablets. You can buy as many pills as your dog needs.

10 and 20 milligrams are the most common, so those are the prices you’ll likely see. One 10-milligram tablet will probably cost you between $0.15 and $0.30. A 20-milligram tablet will cost you between $0.17 to $0.32.

If you want a liquid version instead, it will likely cost you more. Liquid Prednisone comes in larger bottles and can’t be purchased in individual doses. So, even the smallest bottles (15 milliliters) will cost you at least $15. It’s more common to find 30 milliliters or more, which would be $30 and up.

Prednisone Alternatives for Dogs

Licorice : Interestingly, licorice has properties that work like steroids, although not as effective, but does not have many side effects. Medicinal licorice root is often used to treat swelling, itching, and digestive problems in otherwise healthy dogs. The candy licorice will not harm your dog, but the added ingredients are not suitable for long-term health.

Coconut Oil : Coconut oil can help improve your dog’s irritations. Coconut oil has natural antibiotic effects, and it may help reduce a mild infection caused by allergies. Coconut oil also has a lot of antioxidants, which will moisturize your dog’s skin. The itching and irritation may be because the skin is too dry, so using coconut oil will provide relief. Coconut oil also has medium-chain fatty acids, which help improve arthritis symptoms.

Fish Oil : This supplement can help reduce inflammation and itching. The best fish oil to take contains a high level of omega-3 fatty acids, like those found in cold-water fish. Your dog needs omega-3 fatty acids to be healthy.

Turmeric : This spice has been used for thousands of years to fight inflammation caused by arthritis, cancer, pain relief, and skin allergies. You can purchase Turmeric in powder, liquid, or tablet form.

CBD oil for dogs with Arthritis : CBD oil has been shown in some studies and clinical trials to help dogs with arthritis. The studies were small, but the CBD oil helped the dogs. A 2018 clinical trial gave dogs with osteoarthritis 2mg/kg of CBD twice a day, and the dogs’ comfort and activity improved.

CBD oil may help your dog battle pain, stiffness, and swelling in the joints and maintain healthy skin conditions. This will help them feel better and live more comfortably.

How Worms Might Help Your Pet Live 18% Longer

To say Biscuit lived an active life would be an understatement.

Unfortunately, at the age of 10, she started to limp after trips to the dog park. It broke my heart to see her in pain doing what she loved the most. I started feeding her a raw food diet and added high-quality supplements to ensure her nutritional needs were met. Unfortunately, while she loved the food, the limping persisted. I decided to go to the vet. They quickly diagnosed her with osteoarthritis and prescribed a drug to help.

Her limping stopped, and she was in less visible pain. For the first week, it seemed that this was the solution. A few days later, it was to my absolute shock that she.

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