Can Dogs Take Trazodone And CBD Oil

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Overall, CBD use in dogs appears to have a good safety profile and is at low risk for side effects. But “Appears” is the key word here. Being a dog owner isn’t always peachy keen. In fact, sometimes it’s thunder and lightning storms and anxiety attacks……literally. As much as most of us wish our four-legged best friends could talk, this just isn’t the case. When your pup wakes up to scary, loud noises at three in the morning, it’s hard to calm him/h

Which Dogs Should Not Receive CBD?

Continued research is essential to furthering our understanding of how CBD affects the canine body.

Cannabidiol (CBD) is one of over 90 cannabinoids produced by the Cannabis sativa plant and has great potential for therapeutic application in veterinary medicine. The 2018 Farm Bill legalized the regulated production and use of hemp and hemp products that contain less than 0.3% tetrahydrocannabinol (THC) in the United States, and since then, CBD products have become widely available and interest in using CBD to treat our pets is increasing. This is due to not only anecdotal reports, but also scientific evidence of beneficial behavioral and health effects, especially for such conditions as pain (particularly with arthritis), inflammation, anxiety, seizures, and immune system modulation in companion animals.

Overall, CBD use in dogs appears to have a good safety profile and is at low risk for side effects. “Appears” is the key word here, however. Because cannabidiol and other hemp products were federally illegal until 2018, we are only now beginning to see the results of recent scientific studies conducted on these products.

It is known that dogs, like humans, have an endocannabinoid system (a complex cell signaling system); however, experts haven’t yet determined how it all works. Because we are in only the very early stages of understanding just how cannabinoid-based medications affect the canine body, we need to be cautious in administering CBD to our dogs. While we wait for the results of new and ongoing research, here are some key points to be aware of when considering CBD:

  • Currently, there are no veterinary drugs containing CBD that are approved by the United States Food & Drug Administration (FDA). CBD products are currently sold as nutritional supplements and “drug claims” about their use are strictly illegal.
  • There is little documented research, control, or regulation over CBD products. This can result in highly varying compositions, concentrations, and quality, even from one batch to the other of the same product. Because of this, consumers may not know what any individual product contains.
  • A recent study (“Cannabinoid, Terpene, and Heavy Metal Analysis of 29 Over-the-Counter Commercial Veterinary Hemp Supplements”, Vet Med (Auckl). 2020;11:45-55) by Cornell College of Veterinary Medicine and ElleVet Sciences, a manufacturer of pet CBD products, tested 29 CBD pet products. Label guarantees to the cannabinoid concentration contained in the supplement were present on 27 of the 29 products, however, only 10 of the 27 “were within 10% of the total cannabinoid concentrations of their label claim.” Several tested below their label claims of cannabinoid concentration, and two products were found not to contain any CBD at all. Heavy metal contamination was found in four of the products, with lead being the most prevalent contaminant (three products).
  • Owners and veterinarians considering the use of CBD need to be aware of the prevalence of low concentration products. Obtaining a certificate of analysis (COA) from a third party laboratory will enable correct calculation of dosage.
  • There is not yet any data available as to the effects of long-term administration of CBD to dogs. It is also not known if there is any cumulative effect.
  • Of particular concern is any potential interaction between CBD and other medications. Because CBD is metabolized by the cytochrome P450 family of enzymes, it can affect the metabolizing of the other medications in the system. In turn, this can alter the efficacy of these other drugs, either by enhancing their activity or inhibiting the desired activity. Studies with humans have demonstrated that this interaction has impacted drug concentrations in the blood. It has been determined that there is the potential for interaction in humans with the drugs warfarin, tacrolimus, theophylline, ketoconazole, and zonisamide. As these drugs are also used in dogs, it is possible that that there may be interactions in the canine body as well. Other medications that CBD may interfere with include antibiotics, antipsychotics, antidepressants, blood thinners, and any other drugs metabolized by P450 enzymes.
  • Scientific studies have shown that CBD can cause an increase in the liver enzyme alkaline phosphatase (ALP), but the significance of this is not yet known. CBD is thought to be able to enhance the effects of certain drugs. This may present an opportunity or need to reduce the dose of certain medications that are administered to a patient who is also being given CBD.
  • As NSAIDs, Tramadol, Gabapentin, and anti-anxiety drugs rely on P450 enzymes for metabolizing, approach the addition of CBD carefully.
  • When given with trazadone, CBD was found to inhibit the ability of trazodone to lower blood cortisol in a recent study by Morris et al (The Impact of Feeding Cannabidiol [CBD] Containing Treats on Canine Response to a Noise-Induced Fear Response Test, Front. Vet. Sci., 22 September 2020). This highlights the potential drug interactions associated with CBD and may support previous work that shows CBD to be a potent inhibitor of the cytochrome P450 family of enzymes.
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Continued research is essential to furthering our understanding of how CBD affects the canine body. As with any medication, consult your veterinarian before treating your dog with CBD.

Can Dogs Take Trazodone And CBD Oil

Being a dog owner isn’t always peachy keen. In fact, sometimes it’s thunder and lightning storms and anxiety attacks…. literally. As much as most of us wish our four-legged best friends could talk, this just isn’t the case.

When your pup wakes up to scary, loud noises at three in the morning, it’s hard to calm him/her down. While on this topic, fireworks can come out of nowhere for a pup who doesn’t quite understand the concept of July 4th or New Years Eve too.

Loud noises can cause a pup anxiety, it can also cause dangerous situations such as your dog getting scared, running away, or even hurting themselves in the act. Your vet may prescribe anti-anxiety medication to ease your pup’s fear – is it worth it?

While easing your anxious pup, these medications may cause adverse reactions that are maybe worse than hearing fireworks? Yikes. Do you have other options? In this article, we hope to help answer these questions you have and any concerns regarding your pup and those celebratory fireworks.

Fireworks: A Potential Recipe for Disaster

If you’ve ever witnessed a dog become scared from a loud noise, you know how impossible it is to safely calm them down.

Your dog will typically just attempt to escape the situation, running until their legs can’t anymore.

Anxiety Medication

Your vet may prescribe an anti-anxiety medication, if your pup suffers from stress associated with loud noises. We want pet owners to be aware of these medications, what they aim to achieve, and their potential side effects.

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The more you know, the better you can make the best decision possible for your scared pup.

Why Trazodone for Your Dog

Trazodone is a medication typically prescribed to humans as an antidepressant. However, you trazodone is also a medication for dogs. It’s typically seen in the brand names Leptro and Desyrel.

Trazodone for dogs is used as an anti-anxiety medication for the treatment of numerous anxieties including separation anxiety and anxiety provoked by loud sounds. Trazodone inhibits activity at specific serotonin receptor sites in the brain and changes the way the brain receives messages.

Trazodone Side Effects

Sounds like a safe bet for your anxious pet, right? Well, there are some not so great potential side effects of this medication.

  • Sedation
  • Diarrhea
  • Panting
  • Vomiting
  • Hyperactivity
  • Restlessness
  • Agitation
  • Lethargy

You can quickly see numerous of the adverse reactions resemble an anxiety attack. So what’s the point? Giving your pup harsh medication only for it to potentially create more problems doesn’t make much sense.

What is Sileo for Dogs

Sileo is the first and only FDA-approved drug that is designed to treat loud noise anxiety in dogs. Because so many dogs experience anxiety and fear with loud noises, scientists created a medication specifically for the condition. This medication aims to relieve the symptoms of stress associated with those loud noises.

Side Effects of Sileo

Sileo has been advertised to calm your pup without sedation but we can’t ignore dexmedetomidine hydrochloride (the main ingredient). This ingredient is used for heavy sedation. Your pup may also have side effects like abnormally low blood pressure, slow heart action, and sinoatrial arrest.

Unfortunately, there’s more. A sinoatrial arrest can also lead to cardiac arrest, which can lead to death.

Acepromazine for Dogs

Many dogs have noise phobias associated with fireworks, sadly. Many of these dogs are being prescribed a drug called Acepromazine, also known as “Ace”.

This medication is an effective sedative that is used before anesthesia in dogs prior to surgery. But for firework disturbances in your pup, this “Ace” can be very dangerous.

“Ace” Side Effects

  • Seizures
  • Low body temperature
  • Pink-colored urine
  • Hypotension

Valium for your Dog

Valium is often prescribed to humans for anxiety. However, scientists have developed a dosage of valium that your vet may prescribe to ease stress and anxiety associated with loud noises.

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Valium Side Effects

  • Impaired coordination
  • Increased appetite
  • Diarrhea
  • Loss of appetite
  • Fatigue
  • Behavioral changes

Dramamine for Dogs

There are several medications that help ease symptoms associated with stress and anxiety. For example, Dramamine can help with your pup’s motion sickness. It’s an anti-nausea medication, not an anti-anxiety medication. Therefore, your beloved doggo may not be vomiting, but still having high levels of stress.

Your Dog is Terrified: What to Do

Frantically, you’re wondering, what are your options?

Be Prepared

Luckily, we are able to plan ahead, knowing that we know when fireworks typically set off on the same two holidays every year (4th of July and NYE). part of being prepared is understanding symptoms of panic in dogs.

  • Trembling, shaking, hiding, pacing, seeking comfort, erratic behavior
  • Urination, salivation, easily spooked

Be Present

If there’s no way for you to be home with your pup on these loud noise holidays, consider taking your pup to a friend’s place or somewhere that he/she is familiar with and feels safe at.

Stay Calm

Your dog can sense your energy. It’s super important to stay calm. Dogs look to their pack leader (aka you) for social cues.

Desensitize

For weeks leading up to the “big day” holiday, pet owners will desensitize their dogs by playing youtube videos of fireworks. Start off quietly and don’t make a big deal of the fireworks playing in the background. Increasing the volume of videos over time will help reprogram the dog’s mind to not fear the unknown.

How to Calm Your Pup Down Naturally

There are safe and effective ways to naturally calm your anxious pup (with virtually no side effects)!

1. CBD Oil

Studies suggest that CBD oil for your dogs promotes relaxation.

CBD oil can be squirted directly into your pup’s mouth or even mixed into their food.

Here, at Petly CBD, our Pet Hemp Oil is a great choice for your anxious pup! This natural product combines only two natural compounds that support canine health—broad-spectrum hemp extract and MCT coconut oil.

2. CBD Pet Chews

We know some dogs prefer chews over treats. Look no further than these Pet Hemp CBD Dog Treats . Our proprietary veterinarian formulated soft chews are carefully crafted ensuring every ingredient is of the highest quality, and always free of preservatives and pesticides. These tantalizing beef flavored CBD treats not only host a wealth of health benefits, but will have your pup begging for more.

We are pleased that so many of you are finding all-natural, non-toxic results from the powerful CBD herb.

Trazodone for Dogs: Final Thoughts

You want your pup to understand they are safe. Everything is going to be okay and the loud noises will be over soon. Sometimes, it’s just not possible to get these messages across to your pup. Luckily, as pet owners, we can be prepared, present, calm and confident, and implement natural remedies to ensure our pup is comforted and not alone.

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